For a more detailed list of our major employers, click here.

Saint Francis Healthcare Services

Number of Employees: 2817

Hospital

SoutheastHEALTH

Number of Employees: 2430

Hospital

Procter & Gamble Paper Products

Number of Employees: 1200

Mfg. Paper Products

Southeast Missouri State University

Number of Employees: 1107

University

Cape Girardeau Public Schools

Number of Employees: 713

Public Education K-12

Jackson R-2 Schools

Number of Employees: 479

Public Education K-12

Isle Casino Cape Girardeau

Number of Employees: 450

Casino

Mondi Jackson, Inc.

Number of Employees: 428

Flexible Film Packaging

City of Cape Girardeau

Number of Employees: 387

City Government

Delta Companies, Inc.

Number of Employees: 380

Mfg. Stone & Rock

V.I.P. Industries

Number of Employees: 360

Outsourcing

Drury Hotels

Number of Employees: 329

Hotels & Motels

Havco Wood Products

Number of Employees: 315

Oak Flooring Truck Trailers

AT&T Missouri

Number of Employees: 310

Telephone Services

Community Counseling Center

Number of Employees: 310

Mental Health Services

The Lutheran Home

Number of Employees: 300

Home Health/Retirement

MidAmerica Hotels Corporation

Number of Employees: 250

Hotels/Motels/Restaurants

Rhodes 101 Convenience Center

Number of Employees: 250

Convenience Stores

U.S. Postal Service

Number of Employees: 221

Post Office

Exel, Inc.

Number of Employees: 200

Warehousing/Logistics

BioKyowa, Inc.

Number of Employees: 180

Animal Feed Additive

Buzzi Unicem USA

Number of Employees: 180

Mfg. Portland Cement

Missouri Veterans Home

Number of Employees: 180

Long Term Nursing Care

American Railcar

Number of Employees: 175

Mfg. Railcar Parts

Southeast Missourian/Rust Communication

Number of Employees: 170

Newspaper/Printing

Schaefer’s Electrical Enclosures

Number of Employees: 165

Electrical Enclosures

The Rhodes Group

Number of Employees: 160

Commercial/Residential/Storage

Drury Southwest

Number of Employees: 153

Real Estate Development

Newell Rubbermaid

Number of Employees: 150

Closet Accessories & Shelving

Chateau Girardeau

Number of Employees: 140

Retirement

Vizient

Number of Employees: 140

Health Care-Other

RapcoHorizon

Number of Employees: 137

Manufacturer

Schnucks

Number of Employees: 131

Grocery Store

Lowes

Number of Employees: 114

Home Improvement

Chartwells

Number of Employees: 110

Caterer

City of Jackson

Number of Employees: 110

City Government

Life Care Center of Cape Girardeau

Number of Employees: 110

Nursing Home

Heartland Care & Rehab Center

Number of Employees: 105

Nursing & Rehabilitation Center

Cape Girardeau Police Department

Number of Employees: 104

Police

Drury Company

Number of Employees: 100

Contracting Firm

KFVS12/WQWQ-TV

Number of Employees: 100

Television Station

Menards

Number of Employees: 100

Home Improvement

Penzel Construction

Number of Employees: 100

General Contractor

Plaza Tire Service Center

Number of Employees: 100

Automotive-Tires

RM COCO

Number of Employees: 100

Custom Fabric Products

Sam’s Club

Number of Employees: 100

Wholesale Distributor